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Benefits of Using Cannabis CBD Oil, Capsules and Vape Oil

Benefits and Uses of CBD Oil (Plus Side Effects)

Cannabidiol is a popular natural remedy used for many common ailments.

Better known as CBD, it is one of the 104 chemical compounds known as cannabinoids found in the cannabis or marijuana plant, Cannabis sativa.

Tetrahydrocannabinol (THC) is the main psychoactive cannabinoid found in cannabis, and causes the sensation of getting “high” that’s often associated with marijuana. However, unlike THC, CBD is not psychoactive.

This quality makes CBD an appealing option for those who are looking for relief from pain and other symptoms without the mind-altering effects of marijuana or certain pharmaceutical drugs.

CBD oil is made by extracting CBD from the cannabis plant, then diluting it with a carrier oil like coconut or hemp seed oil.

It’s gaining momentum in the health and wellness world, with some scientific studies confirming it may help treat a variety of ailments like chronic pain and anxiety.

Here are seven health benefits of CBD oil that are backed by scientific evidence.

Can Relieve Pain

Marijuana has been used to treat pain as far back as 2900 B.C.

More recently, scientists have discovered that certain components of marijuana, including CBD, are responsible for its pain-relieving effects.

The human body contains a specialized system called the endocannabinoid system (ECS), which is involved in regulating a variety of functions including sleep, appetite, pain and immune system response.

The body produces endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors in your nervous system.

Studies have shown that CBD may help reduce chronic pain by impacting endocannabinoid receptor activity, reducing inflammation and interacting with neurotransmitters.

For example, one study in rats found that CBD injections reduced pain response to surgical incision, while another rat study found that oral CBD treatment significantly reduced sciatic nerve pain and inflammation.

Several human studies have found that a combination of CBD and THC is effective in treating pain related to multiple sclerosis and arthritis.

An oral spray called Sativex, which is a combination of THC and CBD, is approved in several countries to treat pain related to multiple sclerosis.

In a study of 47 people with multiple sclerosis, those treated with Sativex for one month experienced a significant improvement in pain, walking and muscle spasms, compared to the placebo group.

Another study found that Sativex significantly improved pain during movement, pain at rest and sleep quality in 58 people with rheumatoid arthritis

Could Reduce Anxiety and Depression

Anxiety and depression are common mental health disorders that can have devastating impacts on health and well-being.

According to the World Health Organization, depression is the single largest contributor to disability worldwide, while anxiety disorders are ranked sixth.

Anxiety and depression are usually treated with pharmaceutical drugs, which can cause a number of side effects including drowsiness, agitation, insomnia, sexual dysfunction and headache.

What’s more, medications like benzodiazepines can be addictive and may lead to substance abuse

CBD oil has shown promise as a treatment for both depression and anxiety, leading many who live with these disorders to become interested in this natural approach.

In one study, 24 people with social anxiety disorder received either 600 mg of CBD or a placebo before a public speaking test.

The group that received the CBD had significantly less anxiety, cognitive impairment and discomfort in their speech performance, compared to the placebo group.

CBD oil has even been used to safely treat insomnia and anxiety in children with post-traumatic stress disorder

CBD has also shown antidepressant-like effects in several animal studies.

These qualities are linked to CBD’s ability to act on the brain’s receptors for serotonin, a neurotransmitter that regulates mood and social behavior.

Can Alleviate Cancer-Related Symptoms

CBD may help reduce symptoms related to cancer and side effects related to cancer treatment, like nausea, vomiting and pain.

One study looked at the effects of CBD and THC in 177 people with cancer-related pain who did not experience relief from pain medication.

Those treated with an extract containing both compounds experienced a significant reduction in pain compared to those who received only THC extract.

CBD may also help reduce chemotherapy-induced nausea and vomiting, which are among the most common chemotherapy-related side effects for those with cancer.

Though there are drugs that help with these distressing symptoms, they are sometimes ineffective, leading some people to seek alternatives.

A study of 16 people undergoing chemotherapy found that a one-to-one combination of CBD and THC administered via mouth spray reduced chemotherapy-related nausea and vomiting better than standard treatment alone.

Some test-tube and animal studies have even shown that CBD may have anticancer properties. For example, one test-tube study found that concentrated CBD induced cell death in human breast cancer cells.

Another study showed that CBD inhibited the spread of aggressive breast cancer cells in mice.

However, these are test-tube and animal studies, so they can only suggest what might work in people. More studies in humans are needed before conclusions can be made.

May Reduce Acne

Acne is a common skin condition that affects more than 9% of the population.

It is thought to be caused by a number of factors, including genetics, bacteria, underlying inflammation and the overproduction of sebum, an oily secretion made by sebaceous glands in the skin.

Based on recent scientific studies, CBD oil may help treat acne due to its anti-inflammatory properties and ability to reduce sebum production.

One test-tube study found that CBD oil prevented sebaceous gland cells from secreting excessive sebum, exerted anti-inflammatory actions and prevented the activation of “pro-acne” agents like inflammatory cytokines.

Another study had similar findings, concluding that CBD may be an efficient and safe way to treat acne, thanks in part to its remarkable anti-inflammatory qualities.

Though these results are promising, human studies exploring the effects of CBD on acne are needed

Might Have Neuroprotective Properties

Researchers believe that CBD’s ability to act on the endocannabinoid system and other brain signaling systems may provide benefits for those with neurological disorders.

In fact, one of the most studied uses for CBD is in treating neurological disorders like epilepsy and multiple sclerosis. Though research in this area is still relatively new, several studies have shown promising results.

Sativex, an oral spray consisting of CBD and THC, has been proven to be a safe and effective way to reduce muscle spasticity in people with multiple sclerosis.

One study found that Sativex reduced spasms in 75% of 276 people with multiple sclerosis who were experiencing muscle spasticity that was resistant to medications.

Another study gave 214 people with severe epilepsy 0.9–2.3 grams of CBD oil per pound (2–5 g/kg) of body weight. Their seizures reduced by a median of 36.5% .

One more study found that CBD oil significantly reduced seizure activity in children with Dravet syndrome, a complex childhood epilepsy disorder, compared to a placebo.

However, it’s important to note that some people in both these studies experienced adverse reactions associated with CBD treatment, such as convulsions, fever and diarrhea.

CBD has also been researched for its potential effectiveness in treating several other neurological diseases.

For example, several studies have shown that treatment with CBD improved quality of life and sleep quality for people with Parkinson’s disease.

Additionally, animal and test-tube studies have shown that CBD may decrease inflammation and help prevent the neurodegeneration associated with Alzheimer’s disease.

In one long-term study, researchers gave CBD to mice genetically predisposed to Alzheimer’s disease, finding that it helped prevent cognitive decline

Could Benefit Heart Health

Recent research has linked CBD with several benefits for the heart and circulatory system, including the ability to lower high blood pressure.

High blood pressure is linked to higher risks of a number of health conditions, including stroke, heart attack and metabolic syndrome.

Studies indicate that CBD may be a natural and effective treatment for high blood pressure.

One recent study treated 10 healthy men with one dose of 600 mg of CBD oil and found it reduced resting blood pressure, compared to a placebo.

The same study also gave the men stress tests that normally increase blood pressure. Interestingly, the single dose of CBD led the men to experience a smaller blood pressure increase than normal in response to these tests.

Researchers have suggested that the stress- and anxiety-reducing properties of CBD are responsible for its ability to help lower blood pressure.

Additionally, several animal studies have demonstrated that CBD may help reduce the inflammation and cell death associated with heart disease due to its powerful antioxidant and stress-reducing properties.

For example, one study found that treatment with CBD reduced oxidative stress and prevented heart damage in diabetic mice with heart disease.

Several Other Potential Benefits

CBD has been studied for its role in treating a number of health issues other than those outlined above.

Though more studies are needed, CBD is thought to provide the following health benefits:

  • Antipsychotic effects: Studies suggest that CBD may help people with schizophrenia and other mental disorders by reducing psychotic symptoms.
  • Substance abuse treatment: CBD has been shown to modify circuits in the brain related to drug addiction. In rats, CBD has been shown to reduce morphine dependence and heroin-seeking behavior.
  • Anti-tumor effects: In test-tube and animal studies, CBD has demonstrated anti-tumor effects. In animals, it has been shown to prevent the spread of breast, prostate, brain, colon and lung cancer.
  • Diabetes prevention: In diabetic mice, treatment with CBD reduced the incidence of diabetes by 56% and significantly reduced inflammation

The already huge interest in CBD products is expanding. Science and history have confirmed its many benefits. And only quality will distinguish the many brands entering the market. So, let’s look at what could mean to you or those under your care.

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There’s a science to this. Dr. Raphael Mechoulam, the Bulgarian-born Professor of Medicinal Chemistry at Jerusalem’s Hebrew University, has been making breakthrough discoveries since the 1960s. Among his findings is cannabis plants possess hundreds of cannabinoids that mesh with the human natural Endocannabinoid System (ECS). The ECS is an incredibly complex system threading throughout the brain and body including all its systems and glands. The best known and most effective of those cannabinoids are CBD (cannabidiol) and THC (∆9-tetrahydrocannabinol).

THC is a psychoactive agent that binds to CB1 and CB2 receptors in the Central Nervous System (CNS). In doing so, it can trigger mental effects from mild relaxation to creative focus to extreme paranoia. Governments have legislated against the possession and use of THC in cannabis sativa and Indica as a drug.

Hemp is botanically-related to cannabis. Hemp, however, contains little or no THC and its negative effects. This makes its dense CBD content legal and beneficial to thousands with scores of medical issues in the US

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CBD: the mechanism of action

CBD binds with CB1 and CB2 neurotransmitters. Where THC is an agonist, CBD’s chemistry is the opposite. It blocks the interference or intervention of compounds targeting those receptors. And it effectively offsets any influence of THC to help stabilize the flow of neural messages.

CBD runs interference on enzymes that degrade anandamide. Anandamide is a fatty acid amide hydrolase (FAAH) scientists believe is the source of feelings of calm and bliss. The body absorbs anandamide routinely, but stress and pain accelerate the absorption leaving the system imbalanced. But CBD modulates that absorption to manage good moods.

CBD also contributes to an “entourage effect” generating more impact as benefits ride its coattails. That is, while you can trace CBD’s mechanism of action to a certain extent, it appears to carry side benefits not so easily explained.

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CBD: the science studies

Thousands of researches are working on the nature and effects of CBD. But many specifically address known and common physical and psychological conditions. A selected few support its efficacy:

  • Spasticity: Parents have long administered CBD Oil to children afflicted by epilepsy. A 2017 study published in The Journal of Epilepsy Research concluded, “These are exciting times for research in cannabinoids. After almost four millennia of their documented medical use in the treatment of seizure disorders, we are very close to obtaining conclusive evidence of their efficacy in some severe epilepsy syndromes.” Clearly, the purity of the CBD Oil is vital to any pediatric therapy for recalcitrant epilepsy.

Additional research focuses on CBD’s beneficial effect on spasticity related to Muscular Dystrophy, Cerebral Dystrophy, and Multiple Sclerosis. And, some people report benefits for treating muscular pain and cramps linked to Fibromyalgia, Premenstrual Syndrome, Restless Leg Syndrome, and too much physical exercise.

  • Inflammation: Various causes trigger inflammation in muscles, joints, nerves, and body tissue. White blood cells gather at the point of injury to protect it from additional damage. In autoimmune disease, including arthritis, Cystic Fibrosis, diabetic neuropathy, fibromyalgia, lupus, and more, the protective response occurs only to aggravate the problem even when there has been no injury.
    The consequent swelling produces mild to severe chronic pain. Free Radical Biology & Medicine covered a 2011 study reviewing effects of cannabinoids on the oxidation that contributes to inflammation showing the “non-psychotropic cannabinoid cannabidiol, which may interact with the endocannabinoid system but has actions that are distinct, offers promise as a prototype for anti-inflammatory drug development.” That promise also may extend to atherosclerosis, Alzheimer’s disease, hypertension, and depression.
  • Anxiety: CBD has anxiolytic benefits affecting the limbic and paralimbic brain. Administered in oil, capsules, or vaping, CBD modulates blood flow, neural transmission, and nerve sheathing to balance hippocampus rhythms. Research in 2014 in CNS & Neurological Disorders Drug Targets asserted, “Cannabidiol (CBD) is a constituent non-psychotomimetic of Cannabis sativa with great psychiatric potential, including uses as an antidepressant-like and anxiolytic-like compound.”

How CBD produces the calm, rest, and remedy for insomnia remains unclear. But, anecdotal history of its benefit dates back millennia.

There is more science of course on more benefits. Unfortunately, some governance of research has limited studies on animal subjects and restricted long-term human studies.

CBD: oil, capsules, or vape

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How you use CBD is pretty much at your discretion. But CBD oil, capsules, and vape offer options to health-damaging smoking. Each of these methods offers convenience and discrete consumption. But you want to use the best available.

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  • CBD Oil: Consumers and caregivers administer CBD Oil sublingually which speeds its process and effect as sensitive oral tissues absorb its values. Through, you can order dosages at 250mg/bottle, 500mg/bottle, or 1,000mg/bottle and in natural, peppermint, or citrus flavors. It’s offered with the same patient precautions as the capsules, but because it works faster, you should pay attention to its potential to make you drowsy.
  • CBD Capsules: CBD capsules provide a measured serving of CBD oil in a small tasteless pill. Authorized by the MHRA, CBD capsules come 30 capsules to a bottle for a dose of 10mg/capsule. They recommend building dosage after assessing the effects. It is also smart to confer with your doctor regarding interaction with other prescriptions and consumption of grapefruit.
  • CBD Vape Oil: Vaping inhales the vapors of CBD Oil in the vaper’s cartridge. Vaping helps those who are weaning their way off cigarettes as it continues to satisfy the user’s oral fixation. You can even add it to nicotine-infused vape oils. To remain legal in some states in the US, the CBD must contain only trace amounts of THC, even below 0.2%. cbdhemp4real pure-tested vape oil comes in 250mg/bottle and 500mg/bottle doses. They offer the same precautions for use.

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